NATURE’S DEFENSE
INGREDIENTS
Proleviate includes a propriety blend of the highest quality plant-based extracts that create a product line that helps you get back to living a quality life!
The essential oils in Proleviate have soothing benefits attributed to their anti-inflammatory and other valuable properties.
PROLEVIATE’S ACTIVE INGREDIENT
CONOLIDINE
Scientists have shown that a naturally derived painkiller can offer chronic pain treatment.
The pinwheel flower, which is traditionally used in Chinese medicine, interacts with an opioid receptor. Recently identified as ACKR3/CXCR7, this receptor manages the brain’s naturally produced opioid peptides. These are pain receptors that regulate pain relief and emotions.
“The discovery of ACKR3 as a target of conolidine further emphasizes the role of this newly discovered receptor in modulating the opioid system and, consequently, in regulating our perception of pain,” said corresponding author Dr. Andy Chevigné, head of Immuno-Pharmacology and Interactomics at LIH.
“Our findings could also mean that conolidine, and potentially also its synthetic analogues, could carry new hope for the treatment of chronic pain and depression, particularly given the fact that conolidine was reported to trigger fewer of the detrimental side-effects — namely addiction, tolerance and respiratory problems — associated with commonly used opioid drugs like morphine and fentanyl.”
